Contain Levofloxacin 250mg & 500mg tab. This belongs to a group of medicines called antibiotics. Levofloxacin is a ’Fluoroquinolone” antibiotic. Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections, including Gram-(-) and Gram-(+) and atypical bacterial pathogens. Levofloxacin is used alone or in combination with other antibacterial drugs to treat certain bacterial infections including pneumonia, urinary tract infections, and abdominal infections.
Pharmacokinetic Data
Bioavaibility
:
99 %
Protein Binding
:
24 to 38 %
Metabolism
:
Renal
Half Life
:
6 to 8 hours
Excretion
:
Urinary
Mechanism of Action
:
Levofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and iv topoisomerase, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division.
Indications
-
Respiratory infections like A.E.C.B. (Acute esophageal chronic bronchitis)
-
Acute Sinusitis
-
Community Acquired Pneumonia
-
Urinary tract infections like Acute pyelonephritis & Chronic Prostatitis
-
Active Tuberculosis
Dose