Product on VINCIT LifeSciences
Vincit LifeSciences offers world class products and services for various critical illness and diseases. At Vincit LifeSciences, our purpose is to improve the quality of life of the communities we serve.
The products that fall in the Anti-bacterial range are as follows:
Contain Levofloxacin 250mg & 500mg tab. This belongs to a group of medicines called antibiotics. Levofloxacin is a ’Fluoroquinolone” antibiotic. Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections, including Gram-(-) and Gram-(+) and atypical bacterial pathogens. Levofloxacin is used alone or in combination with other antibacterial drugs to treat certain bacterial infections including pneumonia, urinary tract infections, and abdominal infections.
Pharmacokinetic Data
Bioavaibility
:
99 %
Protein Binding
:
24 to 38 %
Metabolism
:
Renal
Half Life
:
6 to 8 hours
Excretion
:
Urinary

 

Mechanism of Action
:
Levofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and iv topoisomerase, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division.

 

Indications
  • Respiratory infections like A.E.C.B. (Acute esophageal chronic bronchitis)
  • Acute Sinusitis
  • Community Acquired Pneumonia
  • Urinary tract infections like Acute pyelonephritis & Chronic Prostatitis
  • Active Tuberculosis

 

Dose
  • O.D.
  • Contain Cefixime 200mg tab. Cefixime is an oral third generation cephalosporin antibiotic used to treat infections caused by bacteria. These include infections of the: Ear (otitis media) Nose, sinuses (sinusitis), Throat (tonsillitis, pharyngitis), Chest and lungs (bronchitis, pneumonia) and Urinary system (Uncomplicated gonorrhea).
    Pharmacokinetic Data
    Bioavaibility
    :
    40 to 50 %
    Protein Binding
    :
    Approximately 60 %
    Absorption
    :
    GI tract
    Half Life
    :
    Average 3 to 4 hours
    Excretion
    :
    Urine & Bile
     
    Indications
    • Otitis Media
    • Pharyngitis & Tonsillitis
    • Acute Bronchitis & A.E.C.B. (Acute esophageal chronic bronchitis)
    • Uncomplicated Gonorrhea
    • Biliary tract infections
     
    Dose
  • B.I.D.
  • Contain Cefpodoxime Proxetil 200mg tab. Cefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative organisms. Cefpodoxime is stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and cephalosporins, due to their production of beta-lactamase, may be susceptible to cefpodoxime. Cefpodoxime is inactivated by certain extended spectrum beta-lactamases.

    The bactericidal activity of cefpodoxime results from its inhibition of cell wall synthesis.

    Pharmacokinetic Data
    Bioavaibility
    :
    50 %
    Protein Binding
    :
    21 to 29 %
    Absorption
    :
    GI tract
    Metabolism
    :
    Liver
    Half Life
    :
    2 hours
    Excretion
    :
    Renal, Unchanged
     
    Indications
    • Pharyngitis or tonsillitis
    • Acute, uncomplicated urethral and cervical gonorrhea
    • Acute, uncomplicated ano-rectal infections in women
    • Uncomplicated skin and skin structure infections
    • Acute maxillary sinusitis
     
    Dose
  • B.I.D.
  • Contains Ofloxacin 200mg & Ornidazole 500mg Combination tab.

    Ofloxacin is a fluorinated 4-quinilone which is effective against several types of bacteria that tend to be resistant to other commonly used antibiotics. It has an in vitro activity against a broad spectrum of gram positive and gram negative and anaerobic bacteria. It exerts its bacterial effect on susceptible microorganisms by entering the bacterial cell and inhibiting a chemical called DNA gyrase which is involved in the production of genetic material DNA. It is indicated for the treatment of genitourinary infections, respiratory infections, gastro intestinal infections.

    Ornidazole is a 5 nitro imidazole which is active against protozoa and anaerobic bacteria. It acts by damage of DNA strands or inhibition of their synthesis. It is indicated for the treatment of several intestinal amoebiasis, hepatic amoebiasis.

    The combination of Ofloxacin and Ornidazole in a fixed dose combination is introduced in India which is having better therapeutics profile and less or negligible side effects. Its composition is each film coated tablet contains Ofloxacin 200mg and Ornidazole 500mg. Both The drug has the category of antibacterial. Ofloxacin and Ornidazole are soluble in water.

    Pharmacokinetic Data
    Bioavaibility
    :
    85 to 95 %
    Protein Binding
    :
    32 %
    Metabolism
    :
    Liver
    Half Life
    :
    8 to 9 hours
    Excretion
    :
    Urine
     
    Indications
    • Giardiasis or Trichomoniasis
    • Most Anaerobic infections
    • Bacterial vaginosis
    • Hepatic or Intestinal Amebiasis
    • Post-surgical infections
    • Orofacial and dental infections.
     
    Dose
  • B.I.D.