BONZI

Active Ingredients
  • CALCIUM CARBONATE
  • CALCITROL
  • ZINC SULPHATE
  • Strength
    500mg+0.25mcg+7.5mg
    Dosage Form
    Soft gel Capsules
    Retail Pack
    1x10 strip
    Bonzi is a combination of Calcitriol which is chemically (5Z,7E)-9,10-secocholesta-5,7,10(19)- triene-1α, 3b,25 -triol, elemental Calcium which is derived from Calcium Carbonate (from Oyster shell) and elemental Zinc derived from Zinc Sulphate (dried).

    Bonzi is a red /Yellow, double coloured, oblong shaped soft gelatin capsule.

    Mechanism of action:
     
    Calcium
    Calcitriol increases intestinal absorption of Calcium , thus giving supplemental Calcium helps in achieving maximum effect of Calcitriol. Calcium as such prevents bone loss in postmenopausal women and is associated with a modest reduction in fracture risk.

    Calcitriol
    Calcitriol stimulates intestinal absorption of Calcium . It exerts negative feedback control on the parathyroid gland through both direct and indirect mechanisms. It directly inhibits
    parathyroid hormone (PTH) secretion and indirectly it increases serum Ca+ which has negative effect on PTH secretion.

    Zinc
    Adequate Zinc is required for normal growth and tissue repair. Urinary elimination of Zinc is increased in osteoporotic women. Zinc depletion is shown to diminish the response of oral Calcitriol when administered orally. Supplementary Zinc not only improves Calcitriol
    response but also helps to arrest bone loss in old postmenopausal women.

     


    Indications
    • Osteoporosis & Osteomalacia
    • Hypo / Hyperparathyroidism
    • Renal Osteodystrophy
    • Fractures / Bone surgery
    • Conditions where additional Calcium is required —PregnancyLactation
     
    Dose
    The recommended daily dose of Bonzi is 1-2 capsules a day as per the requirement of the patients.