CE-DOX
Contain Cefpodoxime Proxetil 200mg tab. Cefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative organisms. Cefpodoxime is stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and cephalosporins, due to their production of beta-lactamase, may be susceptible to cefpodoxime. Cefpodoxime is inactivated by certain extended spectrum beta-lactamases.
The bactericidal activity of cefpodoxime results from its inhibition of cell wall synthesis.
Pharmacokinetic Data
Bioavaibility
:
50 %
Protein Binding
:
21 to 29 %
Absorption
:
GI tract
Metabolism
:
Liver
Half Life
:
2 hours
Excretion
:
Renal, Unchanged
Indications
-
Pharyngitis or tonsillitis
-
Acute, uncomplicated urethral and cervical gonorrhea
-
Acute, uncomplicated ano-rectal infections in women
-
Uncomplicated skin and skin structure infections
-
Acute maxillary sinusitis
Dose