RABEVIN-20
Contains Rabeprazole sodium 20mg (Enteric coated) tab. Rabeprazole is an antiulcer drug in the class of proton pump inhibitors.
Acid is produced naturally in your stomach to help you digest food and to kill bacteria. This acid is irritant so your body produces a natural mucous barrier which protects the lining of your stomach. In some people, this barrier breaks down allowing the acid to damage the stomach, causing inflammation, ulcers and other conditions. In other people there may be a problem with the muscular band at the top of the stomach that keeps the stomach tightly closed. This may allow the acid to escape and irritate the oesophagus. This is called ‘acid reflux’ and can cause heartburn and/or oesophagitis.
Acid is produced naturally in your stomach to help you digest food and to kill bacteria. This acid is irritant so your body produces a natural mucous barrier which protects the lining of your stomach. In some people, this barrier breaks down allowing the acid to damage the stomach, causing inflammation, ulcers and other conditions. In other people there may be a problem with the muscular band at the top of the stomach that keeps the stomach tightly closed. This may allow the acid to escape and irritate the oesophagus. This is called ‘acid reflux’ and can cause heartburn and/or oesophagitis.
Proton pump inhibitors such as rabeprazole stop cells in the lining of the stomach from producing too much acid. This helps to prevent ulcers from forming, or assists the healing process where damage has already occurred. By decreasing the amount of acid, they can also help to reduce the symptoms of acid reflux disease, such as heartburn.
Pharmacokinetic Data
Bioavaibility
:
52 %
Metabolism
:
Non-enzymatic, partly Hepatic
Half Life
:
1 to 1.5 hours
Excretion
:
90 % Renal
Indications
-
Gastric ulcers
-
Peptic ulsers
-
Hyperacidity/ Gastritis due to NSAIDs
-
Healing & Maintenance of Erosive or Ulcerative GERD
-
Treatment of pathological hypersecretory conditions (Zollinger-Ellison syndrome)
-
Helicobacter pylori eradication to reduce risk of duodenal ulcer recurrence
Dose