VINRON

Active Ingredients
  • ONDANSETRON
  • Strength
    2mg
    Dosage Form
    Liquid syrup
    Retail Pack
    30ml
    Contains Ondansetron 2mg / tsp. Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting), often following chemotherapy. It affects both peripheral and central nerves. Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone.

    Pharmacokinetic Data
    Bioavaibility
    :
    ~60 %
    Protein Binding
    :
    70 to 76 %
    Metabolism
    :
    Hepatic
    Half Life
    :
    5 to 7 hours
    Excretion
    :
    Renal
     


    Indications
    • Nausea and Vomiting induced by Cytotoxic chemotherapy and radiotherapy
    • Prevention of post- operative nausea-vomiting
     


    Dose
    Related to Age of Child
  • 6 months to 12 months: 1.6 mg orally every 8 hours.
  • 1 year to 3 years: 3.2 mg orally every 8 hours.
  • 4 years or older: 4 mg orally every 8 hours.